BioBar Camp Day Two

Arrived a little late (wrong exit) as I was twittering while driving.....bad person.

So for now follow @scibarcamp on twitter for this presentation. Or watch biobarcamp on friendfeed.

BioBar Camp Topics Tomorrow

• Cloud computing robotics and future of science
• Interest in Science IP info and who owns data (journals, blogs, data)
• Cell mytochrondia and tools for analysis
• Flow analysis
• Open access open grids/open mac grids; getting resources to users for any sci projects
• Why microbes matter
• Build alternative drug companies (pink army)
• Motivating annotation
• Synthetic biology for space travel (Mars)
• Epernicus (on line communities, what do you need and how to use the existing resources)
• Open Science
• Building the data commons (policy/social issues; funding; tools)
• Article level impact factors vs. journal level impact factor; how measure relevance.
• Biology of aging; philosophical justification of need to study
• Science worship/Science marketing; science as a movement
• Filtering relevance; noise in science
• Boston DIY Bio what's strategic place as a non profit
• Failure in science. What is it, what should it be? Negative data and what is good about it. Alternative careers or accepted path.
• Open Wet Wear. Wiki for science collaboration.
• Comparative Proteogenomics.
• Innovation Automation.
• Neural scanning
• Tracking and using personal data; tracking; little science.
• Personal Health Simulation. CV models and risk and simulate what you could do about it.
• PCR for the People. Developing countries.
• The beginning of neural cognative development of language using MRI. Testable model.
• Nano bay area.
• Payment issue in health care.
• Using web 2.0 tools in companies. Getting beyond the barriers
• Lifeform design contest.
• Biotech Life Sciences Start Up Panel
• Use of machine learning in large genome data sets and where they replicate.
• Impact of researcher unionization (post docs) funding, publications, careers
• Stem cells from perinatal tissue
• 50 years from now: Create incentives to achieve new funding, publishing, new planners, new researchers. What needs to happen today.

BioBar Camp Open Continues

Other models might work. Computer Science values conference method. Impact factors may impeded good science. Need to be published in best journals. But what if cited a bunch from a lesser journal and in print earlier vs. fewer cites in better journal and took longer to get in.



Vocational imperative. But innovation may not come from vocational imperative. It comes from outside who don't have to rationalize choices vocational. They become more a voice. But may miss the boat on vocational imperative.



Business models that work in open? Gateway cloning system. Patent can still be open. Open source actually uses an IP model to facilitate sharing cycles. Negotiation tool.



more info on science commons web site. http://sciencecommons.org/



Is NIH biggest contributor to closed science? They are trying to make money off the IP?

BioBar Camp Open Science What is It.

Kaitlin of Science Commons:
Discussion from ESOF (Euro Science Open Forum??)

1. Access to the content (taxpayer funded research should be open)
2. Access to data (raw data should be available for use)
3. Cyber infrastructure to pull it together (meta data in machine readable format)
4. Access to physical materials (dna, lab mice, etc. MTAs)

In order to replicate.
Open Science is more of a movement vs. Open Source Biology. Open source comes with baggage with license agreements etc. Changing restrictive policies. But software benefits may not work with data.
Suites of tools to use like software development tools (0pen source software as an example). What are the basic needs to do open source biology.
Link between public and science is important. Public supplies lots of data by participating in medical procedures. We don't have a role in influencing what happens with that data, even if it may restrictive. "on behalf of the future of health" May be a PR task, but it is a movement in which the public is vested.

Best practices for the community. Book referenced but didn't get reference.

Open science corporate (IP on the shelves 80% not being used) Behavioral issues as on organization are you open?????Revenue sharing models.

1billion and 17 years to bring a drug to market. But sharing the "dark" data could cut fail rate.

Role of better validation and accountability. Improves the trust network. "Reputation" or "replication" economy.

Piggy back onto peer review? Validation raises the standards in research. Improves science if someone might

What about making the research agenda public. Tons of projects dropped when someone else publishes ahead of you. May increase collaboration.

Rutherford Laboratory

Open Notebook Science.

Currencies being exchanged in the scientific process. Money; desire to contribute to knowledge and change the world; honor/credit/glory. Reconfiguring currencies, make sure that they do still flow.

Peer review is too closed. Why not open it up to improve overall thinking. But where does the attribution currency in up.

IMPACT Factors (is it important to be published in a good journal vs. get published)

watch the example of open source software. Has been a failure. Less than 1% succeeded. But most innovation is a failure. Not a fair standard....

Question is when in the process should open occur and what existing processes stand in the way of advancing science.

BioBar Camp Science to Science Collaboration

Check out this blog regarding science to science collaboration.

http://www.onebiglab.blogspot.com/

Also Toronto BarCamp brought together scientists, doctors, patients, artists. Will find out more about that.

BioBar Camp X2 Project

Cesar Castro introduces X2 project looking for next big disruption in science and technology. Look for more at www.iftf.org.

BioBar Camp "Drive In Heart Surgery"

Stanford cardiologist: What if we did outpatient heart surgery. Stem cell injections. Why not.